Tuberous sclerosis complex and west syndrome: an assessment of cognitive aspects

Background: Tuberous sclerosis complex (TSC) is a genetic disorder characterized by the development of benign tumors in multiple organs and tissues, especially brain, kidneys, heart, lungs, skin. Brain lesions are frequently associated with cognitive deficits, neuropsychiatric disorders, learning disabilities, seizures. Seizures occur approximately 80% patients 30% to 60% them had West Syndrome (WS).